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Casein Kinase II Inhibitor IV
3-(3-(2-(3,4,5-Trimethoxy-phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)propionitrile, Casein Kinase II Inhibitor IV, Keratinocyte Differentiation Inducer
A cell-permeable pyrrolo-pyrimidone compound that acts as a potent, ATP-competitive inhibitor of casein kinase II (IC50 = 9 nM) and an effective inducer of normal human keratinocytes (NHEK) differentiation (EC50 = 100 nM). In addition to CKII, it is also shown to interact, directly or indirectly, with cellular TANK-binding Kinase 1 (TBK1) and NIMA-related kinase 9 (NEK9).
产品信息
Form Beige solid
Molar mass 429.5
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥90% by HPLC
Solubility DMSO or EtOH
Chemical formula C24H23N5O3
CAS number 863598-09-8
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |