Bcl-2 Binding Peptide, Cell-Permeable A cell-permeable peptide that binds to Bcl-2 with high affinity (IC50 = 130 nM in a competition binding study) and induces apoptosis. Displays antitumor activity in cells overexpressing Bcl-2 with no apparent effect on normal peripheral lymphocytes. The peptide is derived from the BH3 domain (residues 140 - 165, a “death domain”) of Bad and is modified to be cell permeant by attaching a decanoyl moiety at the N-terminus. 产品信息 Peptide Sequence CH3(CH2)8CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH Form Off-white solid Formulation Supplied as a trifluoroacetate salt. Molar mass 3399.9 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥95% by HPLC Solubility DMSO Chemical formula C153H240N44O42S 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling