产品说明 A macrolide antibiotic that acts as a specific inhibitor of vacuolar-type H+-ATPase (V-type; Ki = 500 pM). A valuable tool for distinguishing among different types of ATPases. Blocks lysosomal cholesterol trafficking in macrophages and is known to interfere with pH regulation in brain cells. Exhibits cytotoxic effects on a number of cell lines in a cell viability assay. Reported to selectively inhibit β-secretase, an enzyme involved in the processing of amyloid precursor protein (APP). Note: 1 set = 3 x 10 µg 产品信息 Form White solid Primary Target vacuolar type H+ ATPase Primary Target IC50 500 pM Protect from Light 是的 Purity ≥90% by HPLC Chemical formula C35H58O9 CAS number 88899-55-2 Storage -20°C Ship Ambient Temperature Only Carcinogenic / Teratogenic