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L-NMMA . monoacetate
NOS inhibitor
Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).
Product Specification
Alternative Name: NG-Monomethyl-L-arginine . monoacetate
Formula: C7H16N4O2 . CH3COOH
MW: 188.2 . 60.1
CAS: 53308-83-1
Purity: ≥99%
Appearance: White to off-white solid.
Solubility: Soluble in water, 100% ethanol (1mg/ml) or DMSO (0.25mg/ml).
Long Term Storage: +4°C |