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S-Trityl-L-cysteine
Cell cycle blocker
Potent, cell permeable cysteine thioether displaying anti-mitotic and anti-tumor properties. Inhibits mitosis by blocking basal and microtubule-activated ATPase activities of the mitotic kinesin Eg5 (IC50=1µM and 140nm). Induces mitotic arrest in HeLa cells (IC50=700nM) and inhibits the growth of NCI tumor cell line panel (GI50=1.31µM).
Product Specification
Alternative Name: NSC 83265, STLC
Formula: C22H21NO2S
MW: 363.5
CAS: 2799-07-7
RTECS: AY7710000
Appearance: White to off-white solid.
Hazard: HARMFUL.
Solubility: Soluble in DMSO or acetic acid
Long Term Storage: -20°C
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