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Functional Aspects:
Cathepsins are involved in a number of processes including proenzyme activation, enzyme inactivation, antigen presentation, hormone maturation, tissue remodeling and bone matrix resorption. Though controversial, a high level of Cathepsin D in breast cancer may indicate a functional estrogen receptor complex suggesting a likely response to endocrine therapy. This antibody will help detect Cathespsin D in a variety of tissue types. |