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IL-17 Antibody
Product Overview
Antibody Target: Il-17
Alternative Name: IL-17, IL17, IL 17, Interluekin-17, Interluekin 17, interluekin
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: E. coli expressed human IL-17
Accession#: AAC50341
Gene ID: 1155223
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-human IL-17 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 10 mM EDTA, and 0.02% thymersal.
Purification: Affinity purified
Species Reactivity: human
Application: Western blot, Elisa
Application & Usage: Western blot analysis (0.5-1 µg/ml) and ELISA (2-4 µg/ml). However, the optimal conditions should be determined individually.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: IL-17 was identified from a CD4+ T cells DNA library. IL-17 can be induced from primary peripheral blood CD4+ T cells upon stimulation. The cytokine exhibits a high degree of amino acid identity with HVS13, an open reading frame from a T lymphotropic Herpesvirus saimiri and with murine CTLA8. Supernatant from cells transfected with IL-17 induced IL-16 and IL-18 production and enhanced the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. IL-17 is a disulfide-linked homodimer of two 31.0 kDa subunits, each containing 136 amino acid residues.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |