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L6004 SIGMA
Lincomycin hydrochloride
≥90% (TLC)
Synonym: Lincocin hydrochloride, Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride
MSDS SIMILAR PRODUCTS
CAS Number 859-18-7
Empirical Formula (Hill Notation) C18H34N2O6S · HCl
Molecular Weight 443.00
assay ≥90% (TLC)
potency 800-900 units per mg
storage temp. 2-8°C
Description
Biochem/physiol Actions
Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA.3
Mode of action: inhibits bacterial protein synthesis
Antimicrobial spectrum: Gram-positive bacteria
Application
Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding 1,2 Product L6004 is ≥90% (TLC). It is produced by Streptomyces lincolnensis var. lincolnensis and has been used in the treatment of Staphylococcal, Streptococcal, and Bacteroides fragilis infections. |