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G-ODN Control

产品编号: tlrl-godnc     查看说明书
产品名称: G-ODN Control  .0   订购此产品 
供应商: Invivogen
规格: 200 μg
目录价: 1820
库存状态: 三周到货
CAS编号:
应用范围: 生化试验
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G-ODN Control
Negative control for guanosine-rich inhibitory oligonucleotide (TLR9 signaling inhibitor)
G-ODN was suppressive in murine DC and macrophages as well as in human plasmacytoid DC[1].
Inhibitory ODNs act by disrupting the colocalization of CpG ODNs with TLR9 in endosomal vesicles without affecting cellular binding and uptake.
G-ODN Control is a negative control for the suppressive G-ODN.
Specificity: Negative control for G-ODN (murine TLR9 antagonist)
Solubility:  water
G-ODN control sequence
5’- ctc cta ttg tgt gtt tcc tat -3’ (21 mer)
Note: Bases are phosphorothioate (nuclease resistant).
Quality control:
- The absence of bacterial contamination (endotoxins, peptidoglycans) is controlled using HEK-Blue™ TLR2 and HEK-Blue™ TLR4 cells.

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