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Exodus-2, Mouse Recombinant
A chemokine which inhibits hemopoiesis and stimulates chemotaxis
Product Overview
Product Name: Exodus-2, Mouse Recombinant
Alternate Name/Synonyms: C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21
Gene Symbol: CCL21
Accession #: P84444
Gene ID: 18829
Source: E. coli
Appearance: Lyophilized powder
Physical Form Description: Lyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Molecular Weight: 12 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: ≤ 1 EU/μg protein
Biological Activity: The activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
Reconstitution Instructions: Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
Amino Acid Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |