JMJD6 (2-403 aa) (GST-tagged), Human recombinant

JMJD6 (2-403 aa) (GST-tagged), Human recombinant
Functions as a protein hydroxylase or histone demethylase
Product Overview
Product Name: JMJD6 (2-403 aa) (GST-tagged), Human recombinant
Alternate Name/Synonyms: KIAA0585; Jumonji Domain Containing 6; PTDSR1
Gene Symbol: JMJD6
Accession #: Q6NYC1
Gene ID: 23210
Source: E. coli
Appearance: Liquid
Physical Form Description: 50 mM HEPES, pH 7.4, containing 150 mM sodium chloride.
Molecular Weight: 73.2 kDa (2-403 aa, NT GST Tag)
Purity by SDS-PAGE: ≥50%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry ice
Background Information: JMJD6 is a member of the Jumonji C (JmjC)-domain family. This family consists of α-ketoglutarate dependent enzymes which use a cupin fold to coordinate an iron atom. JMJD6 was initially proposed to function as a histone arginine demethylase. Further studies suggest that JMJD6 has hydroxylase activity towards histone tails, the splicing regulatory protein LUC7-Like2, or single-stranded RNA. Recent evidence suggests that JMJD6 gene expression may be a biomarker for aggressive breast cancers.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.