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Core Histones (Human)
Mixture of human core histones involved in gene transcription
Product Overview
Product Name: Core Histones (Human)
Alternate Name/Synonyms: HeLa Core Histones
Gene Symbol: N/A
Accession #: N/A
Gene ID: N/A
Source: Highly purified mixture of human core histones (H2A, H2B, H3, and H4) isolated via hydroxyapatite chromatography from HeLa S3 (human cervical adenocarcinoma) nuclear pellet.
Appearance: Liquid
Physical Form Description: 50 mM sodium phosphate, pH 6.9, containing 10 mM sodium chloride and 1 mM β-mercaptoethanol.
Molecular Weight: N/A
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry ice
Background Information: A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.2 Histone H3 undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |