WRD9 bromodomain 2 (1310-1426 aa) (GST-tagged), Human recombinant

WRD9 bromodomain 2 (1310-1426 aa) (GST-tagged), Human recombinant
A protein regulating the transcription of target promoters
Product Overview
Product Name: WRD9 bromodomain 2 (1310-1426 aa) (GST-tagged), Human recombinant
Alternate Name/Synonyms: BRD and WD repeat-containing protein 1; WD repeat-containing protein 9
Gene Symbol: BRWD1
Accession #: Q9NSI6
Gene ID: 54014
Source: E. coli
Appearance: Liquid
Physical Form Description: 50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.
Molecular Weight: 40.3 kDa (1310-1426 aa + GST Tag)
Purity by SDS-PAGE: ≥85%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry ice
Background Information: The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. WDR9 possesses two bromodomain motifs and eight WD repeats. WDR9 is also known to interact with BRG1 (SMARCA4). This product contains the bromodomain 2 region of WDR9.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.