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Securinine
Description
A g-aminobutyric acid (GABA) receptor antagonist. Recently, it was found to induce apoptosis in human leukemia HL-60 cells.
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Specifications
Cas No. 5610-40-2
Product ID S1609
Product Name Securinine
Chemical Name Securinan-11-one
Formula Wt. 217.26
Melting Point 142-143oC
Purity ≥98%
Solubility Soluble in ethanol 16 mg/mL, DMSO 50 mg/mL. Insoluble in water.
Store Temp +4oC
References Beutler JA, Karbon EW, Brubaker AN et al. Brain Res. 330:135-40 (1985). Dong NZ, Gu ZL, Chou WH, Kwok CY. Chung Kuo Yao Li Hsueh Pao. 20:267-70 (1999).
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