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Andrographolide
Description
Andrographolide is an active principle of the Chinese medicine Andrographis paniculata. It inhibits PAF-induced human blood platelet aggregation, inhibits nitrite synthesis in macrophage, and restores vasocontractile response in thoracic aorta. It protects chemical-induced hepatotoxicity.
Specifications
Cas No. 5508-58-7
Product ID A5313
Product Name Andrographolide
Chemical Name [1R-[1a[E(S*)],4ab,5a,6a,8aa]]-3-[2-[Decahydro-6- hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2- methylene-1-naphthalenyl]ethylidene]dihydro-4- hydroxy-2(3H)-furanone
Synonym Andrographis
Formula Wt. 350.45
Melting Point 218oC-221oC
Purity ≥98%
Solubility Soluble in methanol, acetone, chloroform or ether. Slightly soluble in water.
Store Temp -20oC
References Amroyan, E., Gabrielian, E., Panossian, A., et al. Phytomed. 6:27-31 (1999). Chiou, W.F., Lin, J.J., Chen, C.F. Br. J. Pharmacol. 125:327-334 (1998). Visen, P.K., Shukla, B., Patnaik, G.K., Dhawan, B.N. J. Ethnopharmacol. 40:131-136 (1993). Kapil, A.,
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