Rofecoxib Description Rofecoxib is a cyclooxygenase-2 inhibitor (COX-2) that is used as an anti-inflammatory compound. Specifications Cas No. 162011-90-7 Product ID R5722 Product Name Rofecoxib Chemical Name 4-[4-(Methylsulfonyl)-phenyl]-3-phenyl-2(5H)- furanone Synonym Vioxx Formula Wt. 314.36 Melting Point 207oC-208oC Purity ≥98% Solubility Slightly soluble in methanol and acetone. Insoluble in water. References Catella-Lawson, F. et al. J. Pharmacol. Exp. Ther. 289: 735 (1999).