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Neratinib
Description
It is an orally active, irreversible tyrosine kinase inhibitor of the HER-2 and EGFR.
Specifications
Cas No. 698387-09-6
Product ID N1868
Product Name Neratinib
Chemical Name (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Synonym HKI-272
Formula Wt. 557.04
References Rabindan SK, Discafani CM, Rosfjord EC, et.al. Cancer Res 64:3958-65 (2004). Tsou HR, Overbeek-Klumpers EG, Hallett WA, et.al. J Med. Chem, 48:1107-31 (2005).
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