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Methotrexate
Description
An antineoplastic agent which inhibits dihydrofolate reductase.
Specifications
Cas No. 59-05-2
Product ID M1676
Product Name Methotrexate
Chemical Name N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methyl- amino]benzoyl]-L-glutamic acid
Synonym L-(+)-Amethopterin Dihydrate; Amethopterin; MTX; Emtexate; Ledertrexate; Rheumatrex
Formula Wt. 454.44
Melting Point 185oC-204oC(dec.)
Purity ≥98%
Solubility Practically insoluble in water, or ethanol. Soluble in dilute HCl and in alkaline soln.
Store Temp -20oC
Ship Temp Ambient
References Eckardt, JR Anticancer Drugs. 7:41-6 (1996). Fleisher, M. Ther. Drug Monit. 15:521-6 (1993).
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