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Fluocinolone Acetonide
Description
A synthetic glucocorticoid with anti-inflammatory and anti carcinogenesis properties. It inhibits tumor promotion in mouse skin when applied with a promoting agent at the early stages of promotion. It was also found to inhibit induction of early growth response-1 (Egr-1) gene in SENECAR mice and phospholipid peroxidation in CD1 mice which were exposed to 12-O-tetradecanoyl phorbol-13- acetate (TPA) treatment.
Specifications
Cas No. 67-73-2
Product ID F4582
Product Name Fluocinolone Acetonide
Chemical Name (6a,11
Synonym Coriphate; Dermalar; Fluonid; Fluvean; Jellin; Synalar; Synemol; Synsac
Formula Wt. 452.49
Melting Point 265oC-266oC
Purity ≥98%
Solubility Slightly soluble in water.
Store Temp Ambient
References Digiovanni J, Kruszewski FH, Chenicek KJ. Carcinogenesis. 9:1445-50 (1988). Riggs PK, Rho O, Digiovanni J, Mol. Carcinog. 27:247-51 (2000). Beckman JK, Bagheri F, Ji C, Blair IA, Marnett LJ. Carcinogenesis. 15:2937-44 (1994).
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