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Chymostatin
Description
A highly specific chymotrypsin inhibitor produced by actinomycetes. it also has an anticarcinogeneic property. It was found to supress the incidence of squamous cell carcinomas of the anal gland. The mechanism by which this and other anticarcinogenic protease inhibitors supress carcinogenesis is not fully understood. Presumably these agents inhibit one or more intracellular proteases whose functions are essential for the induction and /or expression of the transformed pheotype.
Specifications
Cas No. 9076-44-2
Product ID C2997
Product Name Chymostatin
Synonym N-(Na-Carbonyl-Cpd-X-Phe-al)-Phe
Formula Wt. 1809.1
Melting Point 276oC-278oC
Purity ≥98%
Solubility Soluble in DMSO.
Store Temp -20oC
References Billings PC, Newberne PM, Kennedy AR. Carcinogenesis. 11:1083-6 (1990). Billings PC, Carew JA, Keller-Mc Gandy CE, Goldberg AL, Kennedy AR. Proc. Nat. Acadamy Sci. 84:4801-5 (1987).
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