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Active Recombinant Human beta-Secretase 1 - BACE-1
A protease important in the formation of myelin sheaths in PNC.
Product Overview
Product Name: Active Recombinant Human beta-Secretase 1 - BACE-1
Alternate Name/Synonyms: Beta-Secretase
Gene Symbol: BACE1
Accession #: P56817
Gene ID: 23621
Source: Insect cell
Appearance: Lyophilized powder
Physical Form Description: Supplied as a lyophilized powder.
Molecular Weight: 47 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: BioVision’s recombinant human beta-Secretase/BACE-1 is biologically active as determined by using the β-Secretase Activity Assay Kit (Cat# K360-100).
Reconstitution Instructions: Use 20 µl sterile D.I. water to dissolve 10 µg of protein for a final conc of 0.5 µg/µl. For further dilution, use 10 mM Tris, pH 8.0.
Storage Temp.: -70°C
Shipping: Gel pack
Background Information: β-Secretase, also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |