E. Coli Recombinant TRXB A protein involved in redox signaling Product Overview Product Name: E. Coli Recombinant TRXB Alternate Name/Synonyms: Thioredoxin reductase Gene Symbol: TRXB Accession #: P0A9P4 Gene ID: 949054 Source: E. coli Appearance: Liquid Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 1mM DTT. Molecular Weight: 34.6 kDa Purity by SDS-PAGE: ≥90% Purity by HPLC: N/A Endotoxin Level: N/A Biological Activity: Specific activity is 4-5 units/ml Reconstitution Instructions: N/A Storage Temp.: -80°C Shipping: Gel pack Background Information: Thioredoxin reductases are the only known enzymes to reduce thioredoxin. Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. Both classes are flavoproteins which function as homodimers. TRXB (Thioredoxin reductase) is a ubiquitous enzyme which is involved in many cellular processes such as cell growth, p53 activity, and protection against oxidation stress. Amino Acid Sequence: MGTTKHSKLL ILGSGPAGYT AAVYAARANL QPVLITGMEK GGQLTTTTEV ENWPGDPNDL TGPLLMERMH EHATKFETEI IFDHINKVDL QNRPFRLNGD NGEYTCDALI IATGASARYL GLPSEEAFKG RGVSACATCD GFFYRNQKVA VIGGGNTAVE EALYLSNIAS EVHLIHRRDG FRAEKILIKR LMDKVENGNI ILHTNRTLEE VTGDQMGVTG VRLRDTQNSD NIESLDVAGL FVAIGHSPNT AIFEGQLELE NGYIKVQSGI HGNATQTSIP GVFAAGDVMD HIYRQAITSA GTGCMAALDA ERYLDGLADA K. Handling: Centrifuge the vial prior to opening USAGE: For Research Use Only! Not For Use in Humans.