E. Coli Recombinant Thioredoxin 1 A protein involved in redox signaling Product Overview Product Name: E. Coli Recombinant Thioredoxin 1 Alternate Name/Synonyms: dasC, fipA, tsnC Gene Symbol: TRXB Accession #: P0A9P4 Gene ID: 949054 Source: E. coli Appearance: Liquid Physical Form Description: 0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 1mM DTT. Molecular Weight: 12.9 kDa Purity by SDS-PAGE: ≥85% Purity by HPLC: N/A Endotoxin Level: N/A Biological Activity: Specific activity is 16-18 A650/min/mg Reconstitution Instructions: N/A Storage Temp.: -80°C Shipping: Gel pack Background Information: Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. It has also recently been found to play a role in cell-to-cell communication. Amino Acid Sequence: MHHHHHHMGS DKIIHLTDDS FDTDVLKADG AILVDFWAEW CGPCKMIAPI LDEIADEYQG KLTVAKLNID QNPGTAPKYG IRGIPTLLLF KNGEVAATKV GALSKGQLKE FLDANLAGS Handling: Centrifuge the vial prior to opening USAGE: For Research Use Only! Not For Use in Humans.