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Human Recombinant PRDX 4
An antioxidant protein implicated in a variety of cellular responses
Product Overview
Product Name: Human Recombinant PRDX 4
Alternate Name/Synonyms: Peroxiredoxin 4, PRX-4, AOE37-2, PRDX4.
Gene Symbol: PRDX4
Accession #: Q13162
Gene ID: 10549
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Molecular Weight: 28.8 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Specific activity: approximately 230-310 pmole/min/µg. Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX 4 and peroxide for 20 min at room temperature.
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: Peroxiredoxin-4 in humans is encoded by the PRDX4 gene. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. It is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappa B.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MWETEERPRT REEECHFYAG GQVYPGEASR VSVADHSLHL SKAKISKPAP YWEGTAVIDG EFKELKLTDY RGKYLVFFFY PLDFTFVCPT EIIAFGDRLE EFRSINTEVV ACSVDSQFTH LAWINTPRRQ GGLGPIRIPL LSDLTHQISK DYGVYLEDSG HTLRGLFIID DKGILRQITL NDLPVGRSVD ETLRLVQAFQ YTDKHGEVCP AGWKPGSETI IPDPAGKLKY FDKLN
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |