|
Human Recombinant PRDX 3
An antioxidant protein implicated in a variety of cellular responses
Product Overview
Product Name: Human Recombinant PRDX 3
Alternate Name/Synonyms: Thioredoxin-dependent peroxide Reductase, mitochondrial, PRDX3, PRX III, Antioxidant protein 1 (AOP-1).
Gene Symbol: PRDX3
Accession #: P30048
Gene ID: 10935
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Molecular Weight: 21.5 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Specific activity: approximately 82-83 pmole/min/µg.
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: Peroxiredoxin-3 (Prdx3) is a mitochondrial member of the antioxidant family of thioredoxin peroxidases that uses mitochondrial thioredoxin-2 (Trx2) as a source of reducing equivalents to scavenge hydrogen peroxide (H2O2). It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Amino Acid Sequence: MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |