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Glutaminase Inhibitor, Compound 968

产品编号: 352010-10MG     查看说明书
产品名称: Glutaminase Inhibitor, Compound 968  .0   订购此产品 
供应商: Merck
规格: ***
目录价: 1,708.00
库存状态: 3周到货
CAS编号:
应用范围: 生化实验
种属来源:
相关信息:

Glutaminase Inhibitor, Compound 968
A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 ≤ 10 µM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells). Shown to effectively shrink tumor size in P-493 B xenografted mouse model (200 µg per inj. i.p., 12 days). Also available as a 10 mM solution in DMSO (Cat. No. 506073).
产品信息
Form  White powder
Molar mass  475.4
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥99% by HPLC
Solubility  DMSO
Chemical formula  C27H27BrN2O
商店和运输信息
Storage  -20°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling

保存条件: -20°C
说明书地址: 点击查看详细
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