NMDA Receptor NR2BCT(1292-1304)-TAT H-KKNRNKLRRQHSY-Ahx-YGRKKRRQRRR-NH2, Tat-NR2BCT A 13-mer NMDA receptor 2B (NR2B) subunit carboxy terminal (1292-1304) derived peptide that specifically binds DAPK1 (death-associated protein kinase 1) in a reversible manner and antagonizes the activated DAPK1-NR2B interaction and the potentiation of NMDAR function with no effect on either the catalytic activity of DAPK1 or the NMDA receptor physiology. Blocks Ca2+ influx through extrasynaptic NMDA receptors (at 50 µM) and the blood-brain-barrier permeable version, namely NR2BCT(1292-1304) attached to TAT(47-57) via a spacer (6-aminohexanoic acid) protects cortical neurons from NMDA receptor-mediated insults and reduces brain infarction and improve neurological functions in mice (10 mg/kg, i.v.). 产品信息 Peptide Sequence H2N-Lys-Lys-Asn-Arg-Asn-Lys-Leu-Arg-Arg-Gln-His-Ser-Tyr-Ahx-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-CONH2 Form White powder Formulation Supplied as a trifluoroacetate salt Molar mass 3382. Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥98% by HPLC Solubility H2O Chemical formula C143H254N64O32 商店和运输信息 Storage -20°C Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice Standard Handling