GPR119 Agonist, AS1269574 A pyrimidine compound that acts as an effective GPR119 agonist (EC50 = 2.5 µM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward β-adrenergic or GLP-1 receptors. Shown to enhance 16.8 mM glucose-induced insulin secretion from murine MIN-6 β-cells (mU/20 min = 0.44 and 0.22, respectively, with or without 10 µM AS1269574) in vitro and improve glucose tolerance in normal mice (100 mg/kg; p.o.) without any significant hypoglycemic effect in vivo. 产品信息 Form Amber solid Molar mass 308.2 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥99% by HPLC Solubility DMSO Chemical formula C13H14BrN3O CAS number 330981-72-1 商店和运输信息 Storage +2°C to +8°C Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice Regulatory Review