InSolution? STAT3 Inhibitor VI, S3I-201

InSolution™ STAT3 Inhibitor VI, S3I-201
A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available.
产品信息
Form  Liquid
Formulation  A 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.
Molar mass  365.4
Protect from Light  是的
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Chemical formula  C16H15NO7S
商店和运输信息
Storage  -20°C
Ship  Dry Ice Only
Irritant