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S1P4 Receptor Antagonist, CYM50358
An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
产品信息
Form White solid
Molar mass 389.28
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥98% by HPLC
Solubility DMSO
Chemical formula C20H18Cl2N2O2
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Regulatory Review |