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Nexturastat A
A potent HDAC6 inhibitor
Product Overview
Product Name: Nexturastat A
Alternate Name/Synonyms: 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide
Description: Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₁₉H₂₃N₃O₃
Molecular Weight: 341.4
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: N/A
InChi: N/A
InChi Key: N/A
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans |