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ITSA-1
A suppressor of Trichostatin A (TSA)
Product Overview
Product Name: ITSA-1
Alternate Name/Synonyms: N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide, ITSA1
Description: Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 200626-61-5
Molecular Formula: C₁₃H₇Cl₂N₃O
Molecular Weight: 292.12
Purity: ≥98% by TLC
Solubility:DMSO (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC=C2C(=C1)N=NN2C(=O)C3=C(C=C(C=C3)Cl)Cl
InChi: InChI=1S/C13H7Cl2N3O/c14-8-5-6-9(10(15)7-8)13(19)18-12-4-2-1-3-11(12)16-17-18/h1-7H
InChi Key: UVNLAUGZMOPBPR-UHFFFAOYSA-N
PubChem CID: 771910
MDL Number: MFCD00195103
USAGE: For Research Use Only! Not For Use in Humans. |