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RO 20-1724
A potent PDEIV inhibitor
Product Overview
Product Name: RO 20-1724
Alternate Name/Synonyms: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Description: Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 29925-17-5
Molecular Formula: C₁₅H₂₂N₂O₃
Molecular Weight: 278.35
Purity: ≥99% by TLC
Solubility:DMSO (~200 mg/ml) or Ethanol (~40 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CCCCOC1=C(C=CC(=C1)CC2CNC(=O)N2)OC
InChi: InChI=1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
InChi Key: PDMUULPVBYQBBK-UHFFFAOYSA-N
PubChem CID: 5087
MDL Number: MFCD00077397
USAGE: For Research Use Only! Not For Use in Humans. |