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Z-FA-FMK
Anirreversible inhibitor of cathepsins B, L, and S
Product Overview
Product Name: Z-FA-FMK
Alternate Name/Synonyms: Benzyloxycarbonyl-Phe-Ala-Fluoromethylketone; Z-Phe-Ala fluoromethyl ketone; Z-Phe-Ala-FMK
Description: Cell-permeable. A useful negative control for FMK-labeled caspase inhibitors. Also, an irreversible inhibitor of cathepsins B, L, and S, and likely cathepsin H, as well as cruzain and papain.
Peptide Sequence: Z-FA-FMK
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 105637-38-5
Molecular Formula: C₂₁H₂₃N₂O₄F
Molecular Weight: 386.42
Purity: ≥95% by HPLC
Solubility:DMSO (20 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and mositure
SMILES: CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
InChi: InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)
InChi Key: ASXVEBPEZMSPHB-UHFFFAOYSA-N
PubChem CID: 122019
MDL Number: MFCD00883668
USAGE: For Research Use Only! Not For Use in Humans. |