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Syk Inhibitor
A potent and reversible Syk inhibitor
Product Overview
Product Name: Syk Inhibitor
Alternate Name/Synonyms: Spleen Tyrosine Kinase Inhibitor
Description: Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC₅₀ = 14 nM). Has been shown to effectively inhibit FcεRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC₅₀ = 313 nM).
Peptide Sequence: N/A
Appearance: Orange solid
Formulation: N/A
CAS Number: 622387-85-3
Molecular Formula: C₁₈H₁₅N₃O₃S
Molecular Weight: 353.39
Purity: ≥97% by HPLC (sum of two isomers)
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and mositure
SMILES: CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC(=C4)S(=O)(=O)N)NC3=O
InChi: InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)/b15-8-
InChi Key: MLKHXLFEYOOYEY-NVNXTCNLSA-N
PubChem CID: 6419747
MDL Number: MFCD07776820
USAGE: For Research Use Only! Not For Use in Humans. |