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Roscovitine
A potent inhibitor of p34cdc2
Product Overview
Product Name: Roscovitine
Alternate Name/Synonyms: 6-Benzylamino-2[(R)-(1'-ethyl-2'-hydroxyethylamino)]-9-isopropylpurine; CYC202; Seliciclib
Description: Cell-permeable. A potent inhibitor of p34cdc2 (IC₅₀ = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 186692-46-6
Molecular Formula: C₁₉H₂₆N₆O
Molecular Weight: 354.45
Purity: ≥98% by HPLC
Solubility: DMSO (~200 mg/ml) or EtOH (~ 200 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
InChi: InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
InChi Key: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
PubChem CID: 160355
MDL Number: MFCD02266401
USAGE: For Research Use Only! Not For Use in Humans. |