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Carbozantinib
A potent inhibitor of MET, VEGFR2, and RET
Product Overview
Product Name: Carbozantinib
Alternate Name/Synonyms: N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Description: Cell-permeable. A potent inhibitor of MET, vascular endothelial growth factor receptor 2 (VEGFR2), and RET, with robust antiangiogenic, antitumor, and anti-invasive effects.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 849217-68-1
Molecular Formula: C₂₈H₂₄FN₃O₅
Molecular Weight: 501.51
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
InChi: InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
InChi Key: ONIQOQHATWINJY-UHFFFAOYSA-N
PubChem CID: 25102847
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |