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SR1001
A high affinity synthetic ligand to retinoic acid-related orphan receptors ɑ (RORɑ) and γt
Product Overview
Product Name: SR1001
Alternate Name/Synonyms: N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide
Description: Cell-permeable. A high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice.
Peptide Sequence: N/A
Appearance: Cream solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₁₅H₁₃F₆N₃O₄S₂
Molecular Weight: 477.4
Purity: ≥98% by TLC and NMR
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: N/A
InChi: N/A
InChi Key: N/A
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |