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Dynasore
A potent dynamin inhibitor
Product Overview
Product Name: Dynasore
Alternate Name/Synonyms: 3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide
Description: Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small GTPases. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addition.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 304448-55-3
Molecular Formula: C₁₈H₁₄N₂O₄ . H₂O
Molecular Weight: 322.31 .18.0
Purity: ≥98% by NMR
Solubility:DMSO (10 mg/ml) or EtOH (1 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC=C2C=C(C(=CC2=C1)C(=O)NNC=C3C=CC(=O)C(=C3)O)O
InChi: InChI=1S/C18H14N2O4/c21-15-6-5-11(7-17(15)23)10-19-20-18(24)14-8-12-3-1-2-4-13(12)9-16(14)22/h1-10,19,22-23H,(H,20,24)/b11-10+
InChi Key: NRQJUIHYFNUXFT-ZHACJKMWSA-N
PubChem CID: 5717066
MDL Number: MFCD11045288
USAGE: For Research Use Only! Not For Use in Humans. |