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Calcitriol
An activator of the vitamin D receptor (VDR)
Product Overview
Product Name: Calcitriol
Alternate Name/Synonyms: 1α, 25-Dihydroxycholecalciferol; 1a,25-Dihydroxyvitamin D3; 25-(OH)2-D3
Description: An active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Known to act as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 32222-06-3
Molecular Formula: C₂₇H₄₄O₃
Molecular Weight: 416.64
Purity: ≥99% by HPLC
Solubility:DMSO (50 mg/ml) or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
InChi: InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChi Key: GMRQFYUYWCNGIN-NKMMMXOESA-N
PubChem CID: 5280453
MDL Number: MFCD00867079
USAGE: For Research Use Only! Not For Use in Humans. |