|
Glibenclamide
An anti-diabetic agent
Product Overview
Product Name: Glibenclamide
Alternate Name/Synonyms: 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide; Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea
Description: Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 10238-21-8
Molecular Formula: C₂₃H₂₈ClN₃O₅S
Molecular Weight: 494
Purity: ≥99% by HPLC
Solubility:DMSO (100 mM) or EtOH (5 mM)
Storage Temp.: 2-8°C
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
InChi: InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
InChi Key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N
PubChem CID: 3488
MDL Number: MFCD00056625
USAGE: For Research Use Only! Not For Use in Humans. |