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Tranilast
A potent angiogenesis inhibitor.
Product Overview
Product Name: Tranilast
Alternate Name/Synonyms: 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid; SB 252218
Description: Cell-permeable. A potent angiogenesis inhibitor. Inhibits VEGF-induced angiogenetic activities. Displays anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 53902-12-8
Molecular Formula: C₁₈H₁₇NO₅
Molecular Weight: 327.33
Purity: ≥98%
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=C(C=C(C=C1)C=CC(=O)NC2=CC=CC=C2C(=O)O)OC
InChi: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
InChi Key: NZHGWWWHIYHZNX-CSKARUKUSA-N
PubChem CID: 5282230
MDL Number: MFCD00864787
USAGE: For Research Use Only! Not For Use in Humans. |