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Salermide
A SIRT1 and SIRT2 inhibitor
Product Overview
Product Name: Salermide
Alternate Name/Synonyms: N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide
Description: Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through reactivation of proapoptotic genes epigenetically repressed exclusively in cancer cells by SIRT1.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 1105698-15-4
Molecular Formula: C₂₆H₂₂N₂O₂
Molecular Weight: 394.47
Purity: ≥98%
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CC(C1=CC=CC=C1)C(=O)NC2=CC=CC(=C2)NC=C3C(=O)C=CC4=CC=CC=C43
InChi: InChI=1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22)27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,27H,1H3,(H,28,30)/b24-17-
InChi Key: UADRPWLRVLBVBC-ULJHMMPZSA-N
PubChem CID: 42626405
MDL Number: MFCD12912446
USAGE: For Research Use Only! Not For Use in Humans. |