|
WHI-P131
A JAK3 inhibitor
Product Overview
Product Name: WHI-P131
Alternate Name/Synonyms: 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Description: Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an IC₅₀ value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 202475-60-3
Molecular Formula: C₁₆H₁₅N₃O₃
Molecular Weight: 297.31
Purity: ≥98% by TLC
Solubility:DMSO (~50mg/ml
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
InChi: InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
InChi Key: HOZUXBLMYUPGPZ-UHFFFAOYSA-N
PubChem CID: 3794
MDL Number: MFCD11045992
USAGE: For Research Use Only! Not For Use in Humans. |