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USP14 Inhibitor, IU1
A USP14 inhibitor
Product Overview
Product Name: USP14 Inhibitor, IU1
Alternate Name/Synonyms: 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
Description: A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC₅₀ = 4-5 µM). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 μM.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 314245-33-5
Molecular Formula: C₁₈H₂₁FN₂O
Molecular Weight: 300.37
Purity: ≥98% by HPLC
Solubility:DMSO (~20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3
InChi: InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
InChi Key: JUWDSDKJBMFLHE-UHFFFAOYSA-N
PubChem CID: 675434
MDL Number: MFCD01917473
USAGE: For Research Use Only! Not For Use in Humans. |