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Calpain Inhibitor II, ALLM
A Calpain inhibitor
Product Overview
Product Name: Calpain Inhibitor II, ALLM
Alternate Name/Synonyms: Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional
Description: A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin’s Lymphoma cells.
Peptide Sequence: N-Acetyl-Leu-Leu-Methional
Appearance: White powder
Formulation: N/A
CAS Number: 136632-32-1
Molecular Formula: C₁₉H₃₅N₃O₄S
Molecular Weight: 401.57
Purity: ≥95% by HPLC
Solubility:DMSO (25 mg/ml) or EtOH (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from moisture and air
SMILES: CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCSC)C=O)NC(=O)C
InChi: InChI=1S/C19H35N3O4S/c1-12(2)9-16(20-14(5)24)19(26)22-17(10-13(3)4)18(25)21-15(11-23)7-8-27-6/h11-13,15-17H,7-10H2,1-6H3,(H,20,24)(H,21,25)(H,22,26)
InChi Key: RJWLAIMXRBDUMH-UHFFFAOYSA-N
PubChem CID: 4331
MDL Number: MFCD00065506
USAGE: For Research Use Only! Not For Use in Humans. |