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Berberine Chloride
An anticancer agent
Product Overview
Product Name: Berberine Chloride
Alternate Name/Synonyms: Natural Yellow 18, 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
Description: An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells that were negative for MDM2 and wt-p53.
Peptide Sequence: N/A
Appearance: Yellow to orange solid
Formulation: N/A
CAS Number: 633-65-8
Molecular Formula: C₂₀H₁₈ClNO₄
Molecular Weight: 371.81
Purity: ≥98% by TLC
Solubility:MeOH (50 mg/ml) or Water (~ 2 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
InChi: InChI=1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChi Key: VKJGBAJNNALVAV-UHFFFAOYSA-M
PubChem CID: 12456
MDL Number: MFCD00011939
USAGE: For Research Use Only! Not For Use in Humans. |