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IKK-ε Kinase Inhibitor II
An IKK-ε kinase inhibitor
Product Overview
Product Name: IKK-ε Kinase Inhibitor II
Alternate Name/Synonyms: 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile
Description: A benzimidazole analog that acts as a potent and selective inhibitor of IKK-ε kinase (IC₅₀ = 40 nM); displays >125-fold selectivity over IKK-α and IKK-β
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 862812-98-4
Molecular Formula: C₂₂H₁₉N₃O₅S₂
Molecular Weight: 469.53
Purity: ≥97% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC
InChi: InChI=1S/C22H19N3O5S2/c1-28-17-8-15-16(9-18(17)292)25(13-24-15)22-10-19(20(11-23)31-22)30-12-14-6-4-5-7-21(14)32(3,26)27/h4-10,13H,12H2,1-3H3
InChi Key: LDTAHRLHGHFHKP-UHFFFAOYSA-N
PubChem CID: 11626927
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |