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AG 1478
A potent EGFR Tyrosine Kinase (TK) inhibitor
Product Overview
Product Name: AG 1478
Alternate Name/Synonyms: 4-(3’-Chloroanilino)-6,7-dimethoxyquinazoline; Tyrphostin AG 1478
Description: Cell-permeable. A potent EGFR Tyrosine Kinase (TK) inhibitor with an IC₅₀ of 3 nM. Only weakly inhibits PDGFR and HER2-NEU kinases (IC₅₀ >100 µM).
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 175178-82-2
Molecular Formula: C₁₆H₁₄ClN₃O₂
Molecular Weight: 315.75
Purity: ≥98% by HPLC
Solubility:DMSO (50 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)CC3=CC(=CC=C3)Cl)OC
InChi: InChI=1S/C17H15ClN2O2/c1-21-16-8-13-14(7-11-4-3-5-12(18)6-11)19-10-20-15(13)9-17(16)22-2/h3-6,8-10H,7H2,1-2H3
InChi Key: DOBKKEHYAFERJH-UHFFFAOYSA-N
PubChem CID: 53429216
MDL Number: MFCD00270914
USAGE: For Research Use Only! Not For Use in Humans |