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LLL12
A Stat3 phosphorylation inhibitor
Product Overview
Product Name: LLL12
Alternate Name/Synonyms: 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
Description: A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.
Peptide Sequence: N/A
Appearance: Lyophilized solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₁₄H₉NO₅S
Molecular Weight: 303.29
Purity: ≥95% by ¹H NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: N/A
InChi: N/A
InChi Key: N/A
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |